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Mesenchymal stem cells as immune cells - Application to inflammatory diseases

Mis en ligne le 24/11/2015

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Multipotent mesenchymal stromal cells (mesenchymal stem cells) [MSCs] are adult stem cells exhibiting functional properties that have been explored for skeletal tissue regeneration. MSCs also exhibit immunosuppressive as well as healing capacities, improving angiogenesis and preventing apoptosis or fibrosis through the secretion of paracrine mediators. This could be useful in the treatment of infl ammatory and degenerative rheumatic diseases and cartilage genetic disorders. Some clinical applications have also been obtained for skeletal tissue repair. Further investigation of the effi cacy and safety of MSCs is needed for current therapeutic uses.

auteur
Pr Christian JORGENSEN
Pr Christian JORGENSEN

Médecin
Rhumatologie
Hôpital Lapeyronie, Montpellier
France
Contributions et liens d'intérêts

centre(s) d’intérêt
Transplantation
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